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Raltitrexed (ZD-1694) is a quinazoline-basedfolate analogue that exerts its cytotoxic activity by the specific inhibition of thymidylate synthase. In vitro studies ...
Raltitrexed DRUG NAME: Raltitrexed SYNONYM(S): Raltitrexed disodium, ZD-1694 COMMON TRADE NAME(S): TOMUDEX® (notice of compliance, 1 September 1996; patent expires2 ...
PHASE II STUDIES A randomized phase II study of raltitrexed and gefitinib versus raltitrexed alone as second line chemotherapy in patients with colorectal cancer.
Introduzca el nombre de la ficha a buscar . ÍNDICE FICHAS TÉCNICAS : ÁCIDO ZOLEDRÓNICO
Chimiothérapie des cancers colo-rectaux avancés Aimery de Gramont, Christophe Louvet, Thierry André, Christophe Tournigand, Eric Raymond, Marcel Krulik
Mechanism. Many are primarily DHFR inhibitors, but raltitrexed is an inhibitor of thymidylate synthase, and pemetrexed inhibits both and a third enzyme.
The staging of colonic carcinoma is the most important determinant of survival rate and is normally expressed via Dukes classification. around half of people ...
Vindesine is an anti-mitotic vinca alkaloid used in chemotherapy. It is used to treat many different types of cancer, including leukaemia, lymphoma, melanoma, breast ...
MANAGEMENT OF EXTRAVASATION: TREATMENT SUMMARY • Extravasation suspected – resistance or absence of free flow, swelling, discomfort, burning,
Définition du sujet et des mots clés : Cancer, Tumor, adenocarcinoma, Colorectal, Colon, Rectal, Metastatic, Diagnostic, Palliative, Treatment, Chemotherapy ...