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Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide  to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.
Probenecid does not influence plasma concentrations of salicylates, nor the excretion of streptomycin, chloramphenicol, chlortetracycline, oxytetracycline, or neomycin. Indications and Usage for Probenecid. Probenecid tablets are indicated for the treatment of the hyperuricemia associated with gout and gouty arthritis.
Find patient medical information for Probenecid Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Probenecid is used to treat gout and gouty arthritis.probenecid reduces the amount of uric acid in your body by causing it to be passed in your urine. Probenecid is also sometimes given together with penicillin antibiotics (including ampicillin, methicillin, oxacillin, cloxacillin, or nafcillin) to make them more effective.. Probenecid may also be used for purposes not listed in this ...
Probenecid - 25G,100G size; Useful as an inhibitor of the organic anion transporter, MRP. Bulk and Prepack available at Sigmaaldrich.com.
Take probenecid exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Probenecid may increase the frequency of gout attacks during the first 6 to 12 months that you take it, although it will eventually prevent them. Another drug, such as colchicine, may be prescribed to decrease this effect.
Probenecid works by decreasing the kidneys' ability to remove the antibiotic from the body.Probenecid should not be used in children younger than 2 years. HOW TO USE: To prevent gout, take this medication by mouth, usually twice daily with food or antacids to reduce stomach upset or as directed by your doctor.
Probenecid is a benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule in the kidney thereby increasing urinary excretion of uric acid and lowering serum urate concentrations. This prevents urate deposition and promotes resolution of existing urate deposits. In addition, probenecid modulates the ...
Probenecid Tablets, USP are available containing 500 mg of Probenecid, USP. The tablets are capsule shaped, film-coated yellow, debossed LCI on one side and 1367 on the other side. They are available as follows:
Probenecid does not cure gout, but after you have been taking it for a few months it will help prevent gout attacks. This medicine will help prevent gout attacks only as long as you continue to take it. Probenecid is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body.