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Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1). On a weight basis it is even more potent than haloperidol.
If you have been taking pimozide on a regular basis and you stop it all of a sudden, you may have signs of withdrawal. Do not stop taking pimozide all of a sudden without calling your doctor. Tell your doctor if you have any bad effects. An unsafe heartbeat that is not normal (long QT on ECG) has happened with pimozide.
Find patient medical information for Pimozide Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Pimozide should only be used to treat people who cannot take other medications or who have taken other medications without good results. Pimozide should only be used to treat severe tics that stop the person from learning, working, or performing daily activities. Pimozide is in a class of medications called conventional antipsychotics.
Pimozide works by changing the actions of chemicals in the brain. Pimozide is used in people with Tourette's syndrome.Pimozide suppresses the physical (motor) and vocal (phonic) symptoms of tics when these symptoms interfere with daily life function.
Consumer information about the medication PIMOZIDE - ORAL (Orap), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug PIMOZIDE - ORAL.
It is also recommended that patients taking pimozide should have an annual ECG (if the QT interval is prolonged, treatment should be reviewed and either withdrawn or dose reduced under close supervision) and that pimozide should not be given with other antipsychotic drugs (including depot preparations), tricyclic antidepressants or other drugs ...
Pimozide versterkt de sederende werking van alcohol, sedativa en slaapmiddelen. Wees voorzichtig met diuretica die aanleiding kunnen geven tot hypokaliëmie. Gelijktijdig gebruik van andere antipsychotica, lithium, antiparkinsonmiddelen, ...
Pimozide: Le pimozide appartient à la classe des médicaments appelés antipsychotiques. Il s'utilise pour prendre en charge les symptômes de certaines formes de schizophrénie chronique. Il agit en influant sur la manière dont les messages sont envoyés dans le système nerveux central.
Identification Name Pimozide Accession Number DB01100 (APRD00218) Type Small Molecule Groups Approved Description. A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.