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Isoniazid, also known as isonicotinylhydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol.
Isoniazid, auch Isonicotinsäurehydrazid, engl. isonicotinic acid hydracide, abgekürzt INH, ist ein bakterizides Antibiotikum, das vor allem in Kombination mit Rifampicin zur Behandlung der Tuberkulose angewendet wird.
Advice and warnings for the use of Isoniazid (Nydrazid) during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out
Physician reviewed isoniazid patient information - includes isoniazid description, dosage and directions.
Background Treatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and elimination. The current standard regimen of isoniazid for 9 months is efficacious but is limited by toxicity and low rates of treatment completion.
It has been known for many years that (IPT) for PLHIV prevents TB. WHO recommends that PLHIV who are unlikely to have active TB should receive at least 6 months of IPT as part of a comprehensive package of HIV care.
This article focuses on acute isoniazid (isonicotinic acid hydrazide [INH]) hepatotoxicity. Since 1952, this agent has been used as a front-line antimicrobial for tuberculosis (TB).
BackgroundIn sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)–associated tuberculosis is high. We conducted a trial with a 2-by-2 factorial design to assess the benefits of early antiretroviral therapy (ART), 6-month isoniazid preventive therapy (IPT), or both among HIV-infected adults with high CD4+ cell counts in Ivory ...
March 2017 1 Fact Sheet: 12-dose Isoniazid (INH)/Rifapentine Regimen for Latent TB Infection Treatment NOTE: It is imperative to rule out active disease in all persons prior to initiating treatment for LTBI
Pharmacokinetics. Isoniazid is quickly and completely absorbed after oral administration; food decreases the absorption and bioavailability of the drug.