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ec·to·ther·mic (ĕk′tə-thûr′mĭk) also ec·to·ther·mal (ĕk′tə-thûr′məl) adj. Of or relating to an organism that regulates its body temperature largely by exchanging heat with its surroundings; cold-blooded. ectothermic (ˌɛktəʊˈθɜːmɪk) adj (of all animals except birds and mammals) having a body temperature that varies ...