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Decitabine (trade name Dacogen), or 5-aza-2'-deoxycytidine, acts as an Nucleic Acid Synthesis Inhibitor. It is a drug for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML).
You must check to make sure that it is safe for you to take decitabine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Decitabine? Tell all of your health care providers that you take decitabine.
How Decitabine Is Given: As an infusion into the vein (intravenous or IV). The actual dosage of Decitabine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition you have.
Eintrag zu Decitabine in der Human Metabolome Database (HMDB), abgerufen am 15. November 2013. FDA Label von Dacogen (PDF; 235 kB). Norbert Gattermann: Epigenetische Behandlung mit 5-Azacytidin und Decitabin, Deutsches MDS-Forum – Duisburg 2008.
Decitabine is a cytosine analogue and an intravenously administered antineoplastic agent used in the therapy of myelodysplastic syndromes. Decitabine is associated with a low rate of transient serum enzyme elevations during therapy, but has not been implicated in causing clinically apparent liver injury with jaundice.
Decitabine (Dacogen) Find out what decitabine is, how you have it and other important information about having decitabine. Decitabine is a chemotherapy drug and is also known by its brand name, Dacogen. It is a treatment for people who can't have the standard chemotherapy for acute myeloid leukaemia.
Decitabine is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Decitabine is in a class of medications called hypomethylation agents. It works by helping the bone marrow
Decitabine is also being studied in the treatment of other conditions and types of cancer. More About Decitabine. Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug. MedlinePlus Information on Decitabine - A lay language summary of important information about this drug that may include the ...
Decitabine for Injection contains Decitabine (5-aza-2’-deoxycitidine), an analogue of the natural nucleoside 2’-deoxycytidine. Decitabine is a fine, white to almost white powder with the molecular formula of C 8 H 12 N 4 O 4 and a molecular weight of 228.21.
Decitabine is a cancer medication that interferes with the growth and spread of cancer cells in the body. Decitabine is used to treat myelodysplastic syndromes (certain types of blood or bone marrow cancer). Decitabine may also be used for purposes not listed in this medication guide.